代表性论文
1. Su W, Saravia J, Risch I, Rankin S, Guy C, Chapman NM, Shi H, Sun Y, Li W, Huang H, KC Anil, Hu H, Wang Y, Liu D, Jiao Y, Chen PC, Soliman H, Yan KK, Zhang J, Vogel P, Liu X, Serrano G, Beach T, Yu J, Peng J, Chi H. CXCR6 orchestrates brain CD8+ T cell residency and limits murine Alzheimer’s disease pathology. Nature Immunology. 2023, 24, 1735-1747. (Research highlight: CD8+ T cells pump the brakes on Alzheimer’s disease. Nature immunology News & Views 2023. 24, 1597-1598.) (Editor’s Choice in Science Signaling: Restraining neuroinflammation in Alzheimer’s disease. Science Signaling. 2023, 16, 808.) (Spotlight in Trends in Immunology: Alzheimer’s defense: brain CD8+ T cells in action. Trends in Immunology. 2023. 12. 936-937)
2. Su W, Chapman NM, Wei J, Zeng H, Dhungana Y, Shi H, Saravia J, Zhou P, Long L, Rankin S, KC Anil, Vogel P, Chi H. Protein prenylation drives discrete signaling programs for the differentiation and maintenance of effector Treg cells. Cell Metabolism. 2020, 32, 996-1011
3. Lim AS*, Su W*, Chapman NM, Chi H. Lipid metabolism in T cell signaling and function. Nature Chemical Biology. 2022, 18, 470-481. * Co-first author
4. Lim AS, Wei J, Ngugen TM, Shi H, Su W, Dhungana Y, Palacios, G, Dhungana, Y, Chapman NM, Long, LL, Saravia, J, Vogel, P, Chi H. Lipid signalling enforces Treg cell functional specialization in tumors. Nature. 2021, 591, 306-311.
5. Blanco B Daniel, Chapman Nicole, Raynor J, Xu C, Su W, KC Anil, Li W, Lim AS, Schattgen S, Shi H, Risch, I, Sun Y, Dhungana Y, Kim YJ, Wei J, Rankin S, Neale G, Thomas P, Yang K, Chi H. PTEN directs developmental and metabolic reprogramming Signaling for innate-like T cell fate and tissue homeostasis. Nature Cell Biology. 2022, 24, 1642-1654.
6. Long L, Wei J, Lim AS, Raynor J, Shi H, Connelly J, Wang H, Guy C, Xie B, Chapman N, Fu G, Wang Y, Huang H, Su W, Saravia J, Risch I, Wang D, Li X, Niu M, Dhungana Y, KC A, Zhou P, Vogel P, Yu Y, Peng M, Pruett-Miller, S, Chi H. CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity. Nature. 2021, 600, 308-313.
7. Zhou M, Li W, Li J, Xie L, Wu R, Wang L, Fu S, Su W, Hu J, Li P. Compartmentalization of Enhanced biomolecular interactions for high-throughput drug screening in test tubes. JBC. 2020, 5.
8. Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H. Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism Underlie IL-7-driven B lymphopoiesis. Sci Adv. 2018, 4