代表性论文
(1) Zhao Y#, Ni W#, Liang S#, Dong L#, Xiang M#, Cai Z#, Niu D#, Zhang Q, Wang D, Zheng Y, Zhang Z, Zhou D, Guo W, Pan Y, Wu X, Yang Y, Jing Z, Jiang Y, Chen Y, Yan H, Zhou Y, Xu K*, Lan K*. Vaccination with Span, an antigen guided by SARS-CoV-2 S protein evolution, protects against challenge with viral variants in mice. Sci Transl Med. 2023 Jan 4;15(677):eabo3332. doi: 10.1126/scitranslmed.abo3332.
(2) Zheng Y, Song K, Cai K, Liu L, Tang D, Long W, Zhai B, Chen J, Tao Y, Zhao Y, Liang S, Huang Q, Liu Q, Zhang Q, Chen Y, Liu Y, Li H, Wang P, Lan K, Liu H*, Xu K*. B-Cell-Epitope-Based Fluorescent Quantum Dot Biosensors for SARS-CoV-2 Enable Highly Sensitive COVID-19 Antibody Detection. Viruses. 2022 May 12;14(5):1031.
(3) Zheng Y, Li S, Song K, Ye J, Li W, Zhong Y, Feng Z, Liang S, Cai Z, Xu K*. A Broad Antiviral Strategy: Inhibitors of Human DHODH Pave the Way for Host-Targeting Antivirals against Emerging and Re-Emerging Viruses. Viruses. 2022 Apr 28;14(5):928.
(4) Bai L#, Zhao Y#, Dong J#, Liang S#, Guo M#, Liu X, Wang X, Huang Z, Sun X, Zhang Z, Dong L, Liu Q, Zheng Y, Niu D, Xiang M, Song K, Ye J, Zheng W, Tang Z, Tang M, Zhou Y, Shen C, Dai M, Zhou L, Chen Y, Yan H, Lan K*, Xu K*. Coinfection with influenza A virus enhances SARS-CoV-2 infectivity. Cell Res.2021 Apr;31(4):395-403.
(5) Xiong R#, Zhang L#, Li S#, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H*, Xu K*. Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein&Cell. 2020 Oct;11(10):723-739.
(6) Hu K*, Wang M, Zhao Y, Zhang Y, Wang T, Zheng Z, Li X, Zeng S, Zhao D, Li H, Xu K*, Lan K*. A Small-Scale Medication of Leflunomide as a Treatment of COVID-19 in an Open-Label Blank-Controlled Clinical Trial. Virol Sin. 2020 Jul, 35(6):725-733.
(7) Ping X, Hu W, Xiong R, Zhang X, Teng Z, Ding M, Li L, Chang C, Xu K*. Generation of a broadly reactive influenza H1 antigen using a consensus HA sequence. Vaccine. 2018 Aug 6;36(32 Pt B):4837-4845.
(8) Shan J#, Zhao B#, Shan Z#, Nie J, Deng R, Xiong R, Tsun A, Pan W, Zhao H, Chen L, Jin Y, Qian Z, Lui K, Liang R, Li D, Sun B, Lavillette D, Xu K*, Li B*. Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation. PLoS Pathog. 2017 Dec 13:12:e1006773.
(9) Giese S#, Ciminski K#, Bolte H, Moreira ÉA, Lakdawala S, Hu Z, David Q, Kolesnikova L, Götz V, Zhao Y, Dengjel J, Chin YE*, Xu K*, Schwemmle M*. Role of influenza A virus NP acetylation on viral growth and replication. Nature Communications. 2017 Nov 2;8(1):1259.
(10)Zhang H, Han Q, Ping X, Li L, Chang C, Chen Z , Shu Y, Xu K*, Sun B*. A single NS2 mutation of K86R promotes PR8 vaccine donor virus growth in Vero cells. Virology, 2015 Aug ,482: 32–40
(11)Hu W, Zhang H , Han Q , Li L , Chen Y , Xia N , Chen Z , Shu Y , Xu K*, Sun B*. A Vero-cell-adapted vaccine donor strain of influenza A virus generated by serial passages. Vaccine, 2015 Jan 33；2(3):374-381
(12) Han Q, Chang C, Li L, Klenk C, Cheng J, Chen Y, Xia N, Shu Y, Chen Z, Gabriel G, Sun B*, Xu K*. Sumoylation of influenza a virus nucleoprotein is essential for intracellular trafficking and virus growth. Journal of Virology, Spotlight Paper. 2014 Aug 15;88(16):9379-90.
(13) Zhang H, Hale BG, Xu K*, Sun B*. Viral and host factors required for avian H5N1 influenza A virus replication in mammalian cells. Viruses. 2013 Jun 10;5(6):1431-1446.
(14) Xu K, Klenk C, Liu B, Keiner B, Cheng J, Zheng BJ, Li L, Han Q, Wang C, Li T, Chen Z, Shu Y, Liu J, Klenk HD, Sun B. Modification of Nonstructural Protein 1 of Influenza A Virus by SUMO1. Journal of Virology, 2011, Jan. 85(2):1086–98.
(15) Xu K, Ling ZY, Sun L, Xu Y, Bian C, He Y, Lu W, Chen Z, Sun B. Broad humoral and cellular immunity elicited by a bivalent DNA vaccine encoding HA and NP genes from a H5N1 virus. Viral Immunol, 2011 Feb; 24(1):45-56.
(16) He Y#, Xu K#, Keiner B, Zhou J, Czudai V, Li T, Chen Z, Liu J, Klenk HD, Shu YL, Sun B. Influenza A virus replication Induces Cell Cycle Arrest in G0/G1 Phase. Journal of Virology, 2010, Dec; 84(24):12832-40.
Xu K, Zheng BJ, Zeng R, Lu W, Lin YP, Xue L, Li L, Yang LL, Xu C, Dai J, Wang F, Li Q, Dong QX, Yang RF, Wu JR, Sun B. Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein. Virology, 2009, 388:279-285.
