代表性论文
1. W Han#, HY Qiu#, S Sun#, ZC Fu#, GQ Wang#, X Qian, L Wang, X Zhai, J Wei, Y Wang, YL Guo, GH Cao, RJ Ji, YZ Zhang, H Ma, H Wang, M Zhao, J Wu, L Bi, QB Chen, Z Li, L Yu, X Mou, H Yin, L Yang *, J Chen *, B Yang *, Y Zhang *. Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable offtarget mutations in human HSCs. Cell Stem Cell, 30,1-16, Dec 7th, 2023
2. J An #, CP Zhang#, HY Qiu#, HX Zhang#, QB Chen, YM Zhang, XL Lei, CX Zhang, H Yin*, Y Zhang*. Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS-STING pathway. Nature Biomedical Engineering, July 27, 2023
3. CP Zhang, HY Qiu, CX Zhang, YM Zhang, YZ Zhang, H Yin, KQ Zhang*, Y Zhang*. Efficient non-viral delivery of macromolecules in human primary hematopoietic stem cells and lymphocytes. Journal of Molecular and Cell Biology, 2023 Aug 3;15(3)
4. HX Zhang#, CX Zhang#, SH Lu, XH Tong, K Zhang, H Yin*, Y Zhang*. Cas12a-based one-pot SNP detection with high accuracy. Cell Insight, (2023): 100080. doi.org/10.1016/j.cellin.2023.100080
5. HY Qiu, RJ Ji, Y Zhang*. Current advances of CRISPR-Cas technology in cell therapy. Cell Insight, (2022): 100067 doi.org/10.1016/j.cellin.2022.100067
6. YJ Shi#, M Duan#, JM Ding#, FQ Wang, LL Bi, CX Zhang, YZ Zhang, JY Duan, AH Huang, XL Lei, H Yin, Y Zhang*. DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near PAMless cleavage by thermophilic Cas9. Molecular Cell, Nov 3;82(21):4160-4175, 2022
7. SH Lu#, XH Tong#, Y Han#, K Zhang, YZ Zhang, QB Chen, JY Duan, XL Lei, MH Huang, Y Qiu, DY Zhang, X Zhou, Y Zhang* and Hao Yin*. Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a. Nature Biomedical Engineering, 2022 Mar;6(3):286-297, 2022
