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两院院士

朱玉贤

邮          箱:Zhuyx@whu.edu.cn

职          称:教授

办公室地址:

实验室地址:武汉大学生命科学学院5102室

个人简介

个人介绍

浙江富阳人,著名植物生理学家、中国科学院院士、发展中国家科学院院士、教育部长江学者奖励计划特聘教授、国家杰出青年科学基金获得者。

教育经历

1982年7月毕业于浙江农业大学农学系

1989年12月于美国康奈尔大学获得博士学位

工作经历

1989年博士毕业后,先后在美国华盛顿大学和北京大学从事博士后研究

1994年7月至今,任北京大学生命科学学院教授、博士生导师

2014年至今,任武汉大学生命科学学院教授、博士生导师,武汉大学高等研究院院长。

荣誉奖励

首届全国教材建设奖二等奖:《现代分子生物学》第5版

何梁何利科学与技术进步奖,2012

国家自然科学二等奖,2011

国家级教学成果奖二等奖,2009

教育部自然科学一等奖,2008

教育部科技进步二等奖,2000

中国国家科技图书奖提名奖,1999

社会服务

先后兼任中国植物生理与植物分子生物学学会副理事长,《中国科学:生命科学》常务副主编,农业生物技术国家重点实验室学术委员会主任,农作物基因组学国家重点实验室、作物生物学国家重点实验室、棉花生物学国家重点实验室学术委员会委员。2013年至今任教育部大学生物学课程教学指导委员会主任,农业部转基因生物新品种培育重大专项总体组技术副总师,主持多项国家级重大科研项目。

科研领域

主要从事植物生理学和基因组学研究,在棉纤维发育分子机制和拟南芥转录调控因子研究等方面做出了显著贡献。首次发现植物激素乙烯参与调控棉纤维伸长,揭示了纤维细胞发育的分子机制,为大幅度提高棉纤维品质提供了理论依据;测序并组装了二倍体棉花D基因组、A基因组及四倍体棉花AD基因组,充分解析了棉花A亚基因组起源之谜;成功构建了高质量陆地棉胚珠cDNA文库,建成具有国际领先水平的大型高通量陆地棉cDNA芯片,获得了纤维伸长时期的基因表达谱;与国内外11家实验室合作克隆了1282个拟南芥转录调控因子基因,找到了一批可能参与调控各种生理过程的受不同环境条件或处理诱导表达的转录调控因子基因;所主编的《现代分子生物学》发行超过50万册,成为我国大学生物学专业本科生分子生物学首选教材和国家“十一五”至今规划教材,也是研究生入学考试中有关分子生物学课程最广泛认可的参考书。

代表性论文

  1. Huang G, Huang JQ, Chen XY,Zhu YX#. Recent advances and future perspectives in cotton research.Annual Review of Plant Biology72:2.1–2.26. IF: 26.379 引用:2

  2. Wen XP, Huang G, Li CY andZhu YX#(2021) A Malvaceae-specific miRNA targeting the newly duplicated GaZIP1L to regulate Zn2+ion transporter capacity in cotton ovules.Sci. china life Sci.,64:339-351. IF: 6.038 引用: 0

  3. Huang G, Wu Z, Percy RG, Bai M, Li Y, Frelichowski JE, Hu J, Wang K, Yu, JZ,Zhu YX#(2020) Genome sequence of Gossypium herbaceum and genome updates of Gossypium arboreum and Gossypium hirsutum provide insights into cotton A-genome evolution.Nature Genetics., 52:515-524. IF: 38.33 引用: 39

  4. Wang, K., Wang, D., Zheng, X., Qin, A., Zhou, J., Guo, B., Chen, Y., Wen, X., Ye, W., Zhou, Y.,Zhu, YX#(2019). Multi-strategic RNA-seq analysis reveals a high-resolution transcriptional landscape in cotton.Nature Communications, 10: 4714. IF: 14.919 引用: 15

  5. Zhang YZ, Jiao Y, Jiao HY, Zhao HB,Zhu YX#. (2017) Two-step functional innovation of the stem-cell factors WUS/WOX5 during plant evolution.Mol. Biol. Evol.34: 640-653. IF:16.24 引用: 23

  6. Li, F.G., Fan, G.Y., Lu, C.R., Xiao, G.H., Zou, C.S., Kohel, R.J., Ma, Z.Y., Shang, H.H., Ma, X.F., Wu, J.Y., Liang, X.M., Huang, G., Percy, R.G., Liu, K., Yang, W.H., Chen, W.B., Du, X.M., Shi, C.C., Yuan, Y.L., Ye, W.W., Liu, X., Zhang, X.Y., Liu, W.Q., Wei, H.L., Wei, S.J., Huang, G.D., Zhang, X.L., Zhu, S.J., Zhang, H., Sun, F.M., Wang, X.F., Liang, J., Wang, J.H., He, Q., Huang, L.H., Wang, J., Cui, J.J., Song, G.L., Wang, K.B., Xu, X., Yu, J.Z.,Zhu, Y.X#., Yu S.X.. (2015) Genome sequence of cultivated Upland cotton (Gossypium hirsutumTM-1) provides insights into genome evolution.Nat.Biotechnol, 33: 524-530. IF: 54.908 引用: 635

  7. Zhang, Y.Z., Jiao, Y., Liu, Z.H.,Zhu, Y.X#. ROW1 maintains quiescent centre identity by confining WOX5 expression to specific cells.Nature Communications 2015 doi: 10.1038/ncomms7003. IF:14.919引用: 81

  8. Li, F.G., Fan, G.Y., Wang, K.B., Sun, F.M., Yuan, Y.L., Song, G.L., Li, Q., Ma, Z.Y.,Lu,C.R., Zou, C.S., Chen, W.B., Liang, X.M., Shang, H.H., Liu, W.G., Shi, C.C., Xiao, G.H., Gou, C.Y., Ye, W.W., Xu, X., Zhang, X.Y., Wei, H.L., Li, Z.F., Zhang, G.Y., Wang, J.Y., Liu, K. Kohel, R.J.,Percy, R.G., Yu, J.Z.,Zhu,Y.X#., Wang, J. Yu, S.X..Genome sequence of the cultivated cotton Gossypium arboreum .Nature Genetics 46 (2014), 567-572.IF:38.33引用:594

  9. Li, Q., Xiao, G. H., andZhu, Y. X#.Single-nucleotide resolution mapping of theGossypium raimondiitranscriptome reveals a new mechanism for alternative splicing of introns.Molecular Plant, 7 (2014), 829-840.IF:13.164引用: 44

  10. Wang, K. B., Wang, Z. W., Li, F. G., Ye, W. W., Wang, J. Y., Song, G. L., Yue, Z., Cong, L.,Shang, H.H.,Zhu, S. L., Zou, C. S., Li, Q., Yuan, Y. L., Lu, C. R., Wei, H. L., Gou, C. Y., Zheng, Z. Q., Yin, Y., Zhang,X. Y., Liu, K., Wang, B., Song, C., Shi, N., Kohel, R. J., Percy, R. G., Yu, J. Z.,Zhu, Y. X#., Wang, J. andYu, S. X. The draft genome of a diploid cottonGossypium raimondii.Nature Genetics (Nat. Genet.) 44 (2012), 1098-1103. IF: 38.33引用: 707

  11. Pang, C.Y., Wang, H., Pang, Y., Xu, C., Jiao, Y., Qin, Y.M., Western, T.L., Yu, S.X. andZhu,Y.X#. Comparative proteomics indicate that biosynthesis of pectic precursors is important for cotton fiber and Arabidopsis root hair elongation.Molecular Cellular Proteomics (Mol. Cell. Proteomics), 9 (2010), 2019-2033. IF:5.911 引用: 129

  12. Han, P., Li, Q. andZhu, Y. X#. Mutation of Arabidopsis BARD1 causes meristem defects by failing toconfine WUSCHEL expression to the organizing center.Plant Cell 20 (2008), 1482-1493. IF: 11.277引用: 61

  13. Qin, Y. M., Hu, C. Y., Pang, Y., Kastaniotis, A. J., Hiltunen, J. K. andZhu, Y. X#. Saturated very-long-chain fatty acids promote cotton fiber and Arabidopsis cell elongation by activating ethylene biosynthesis.Plant Cell 19 (2007), 3692-3704. IF:11.277 引用:197

  14. Qu, L. J. andZhu, Y. X#. Transcription factor families inArabidopsis: major progress and outstanding issues for future research. Curr. Opin.Plant Biol. (CURR OPIN PLANT BIOL) 9 (2006), 544-549. IF: 7.834引用: 141

  15. Shi, Y. H., Zhu, S. W., Mao, X., Feng, J. X., Qin, Y. M., Zhang, L., Cheng, J., Wei, L., Wang, Z. Y. andZhu, Y. X#. Transcriptome profiling, molecular biological and physiological studies reveal a major role for ethylene in cotton fiber cell elongation.Plant Cell 18 (2006), 651-664. IF:11.277 引用: 466

  16. Qin, Y. M., Pujol, F. M. A., Shi, Y. H., Feng, J. X., Liu, Y. M., Kastaniotis, A. J., Hiltunen, J. K. andZhu,Y. X#. Cloning and functional characterization of two cDNAs encoding NADPH-dependent 3-ketoacyl-CoA reductases from developing cotton fibers.Cell Res. 15 (2005), 465-473. IF: 25.617 引用:44

  17. Gong, W., Sun, Y. P., Ma, L. G., Pan, Y., Du, Y. L., Wang, D. H., Yang, J. Y., Hu, L. D., Liu, X. F., Dong, C. X., Ma, L., Chen, Y. H., Yang, X. Y., Gao, Y., Zhu, D. M., Tan, X. L., Mu, J. Y., Zhang, D. B., Liu, Y. L., Dinesh-Kumar, S. P., Li, Y., Wang, X. P., Gu, H. Y., Qu, L. J., Bai, S. N., Lu, Y. T., Li, J. Y., Zhao, J. D., Zuo, J. R., Huang, H., Deng, X. W. andZhu, Y. X#. Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes.Plant Physiol. 135 (2004), 773-782. IF: 8.34 引用: 236

  18. Ji, S. J., Lu, Y. C., Feng, J. X., Wei, G., Li, J., Shi, Y. H., Fu, Q., Liu, D., Luo, J. C. andZhu, Y. X#.Isolation and analyses of genes preferentially expressed during early cotton fiber development by subtractive PCR and cDNA array.Nucleic Acids Res. 31 (2003), 2534-2543. IF:16.971 引用:225

  19. Zhu, Y. X*., Tepperman, J. M., Fairchild, C. and Quail, P. H. Phytochrome B binds with greater apparent affinity than phytochrome A to the basic helix-loop-helix factor PIF3 in a reaction requiring the PAS domain of PIF3. Proc. Natl. Acad. Sci. USA. (P NATL ACAD SCI USA) 97 (2000), 13419-13424. IF: 11.205 引用: 113

实验室简介

研究方向 棉花基因组、比较基因组及演化研究;棉纤维发育功能基因组学和拟南芥转录调控因子研究 邮箱 Zhuyx@whu.edu.cn
职称 教授 办公室地址
实验室地址 武汉大学生命科学学院5102室