Biography

Working Experience:

2015-present, Wuhan University, Professor

2011-2015, the Scripps Research Institute (with Prof. Phil S Baran)

2010-2011, SIOC, Research Associate (with Prof. Dawei Ma)

Education and Training:

2005-2010, Shanghai Institute of Organic Chemistry, PhD (supervisor Prof. Dawei Ma)

2001-2005, Peking University, BS (supervisor Prof. Jinguang Wu and Prof. Weihong Li)

Research

We actively explore at both synthetic tactics level and novel synthetic methodologies level towards specific target natural products. Our current four directions are:

1. Target oriented novel synthetic methodology and tactic development, especially focusing on cascade and multicomponent transformations.

2. Efficient and practical (scalable) synthesis of highly valued natural products to enable a meaningful supply.

3. Quick construction of NP analogs and derivative libraries based on efficient synthetic strategy, and systematically explore related structure/function relationships, target identification studies, and medicinal chemistry through collaboration.

4. Process chemistry development for important medicines.

Representative  Publications

1. Cheng, H.-G.^#; Jia, S.^#; Zhou, Q.^* Acc. Chem. Res. 2023, 56, 573.

2. Zhou, L.^#; Cheng, H.-G.^#,^*; Li, L.; Wu, K.; Hou, J.; Jiao, C.; Deng, S.; Liu, Z.; Yu, J.-Q.^*; Zhou, Q.^* Nat. Chem. 2023, 15, 815.

3. Song, F.^#; Zheng, M.^#, Wang, J.; Liu, H.; Lin, Z.; Liu, B.; Deng, Z.; Cong, H.; Zhou, Q.^*; Qu, X.^* Nat. Synth. 2023, 2, 729.

4. Liu, Z.-S.; Hua, Y.^#; Gao, Q.^#; Ma, Y.; Tang, H.; Shang, Y.; Cheng, H.-G.; Zhou, Q.^* Nat. Catal. 2020, 3, 727.

5. Wang, J.^#; Zhang, Y.^#; Liu, H.; Shang, Y.; Zhou, L.; Wei, P.; Yin, W.-B.; Deng, Z.; Qu, X.^*; Zhou, Q.^* Nat. Commun. 2019, 10, 3378.

6. Gao, Q.; Shang, Y.; Song, F.; Ye, J.; Liu Z.-S.; Li, L.; Cheng, H.-G.; Zhou, Q.^* J. Am. Chem. Soc. 2019, 141, 15986.

7. Chen, S.^#; Liu, Z.-S.^#; Yang, T.; Hua, Y.; Zhou, Z.; Cheng, H.-G.; Zhou, Q.^* Angew. Chem. Int. Ed. 2018, 57, 7161.