Biography

Working Experience:

2023.03-present Professor, Wuhan University

2022.02-2023.02 Postdoc, Münster Universität, Advisor: Prof. Armido Studer

2018.09-2021.12 Postdoc, Max-Planck-Institut für Kohlenforschung, Advisor: Prof. Tobias Ritter

Education:

2013.09-2018.06 Ph.D. in Organic Chemistry, Shanghai Institute of Organic Chemistry, CAS, Advisor: Prof. Shu-Li You

2009.09-2013.06 B.S. in Chemistry, Sichuan University

Research

Research in the Cheng group lies within the development of new catalysts, new reagents and new methods, aiming at challenging synthetic problems. We develop methodologies that expand the scope and sustainability of synthetic chemistry using the unique capabilities of photochemistry. Particularly, we focus our research on challenging carbon-heteroarom bond formation reactions that leads to the synthesis of valuable organic molecules.

The main research areas include:

Organofluorination, [18F]Fluorination, Photochemistry, Free Radical Reactions

Representative  Publications

1. Zhang, J.;# Wang, J.;# Cheng, Q.* "Recent advances in C–F bond formation from carbon-centered radicals." Chin. J. Chem. 2024, DOI: 10.1002/cjoc.202300580. (#co-first author)

2. Cheng, Q.;# Bhattacharya, D.;# Haring, M.; Cao, H.; Mück-Lichtenfeld, C.; Studer, A.* “Skeletal Editing of Pyridines through Atom Pair Swap from CN to CC.” Nat. Chem. 2024, DOI：10.1038/s41557-023-01428-2. (#co-first author)

3. Cao, H.;# Cheng, Q.;# Studer, A.* “Radical and ionic meta-C–H functionalization of pyridines, quinolines, and isoquinolines.” Science 2022, 378, 779–785. (#co-first author)

4. Cheng, Q.; Tewari, S.; Ritter, T.* “Bifunctional Sulfilimines Enable Synthesis of Multiple N-Heterocycles from Alkenes.” Nat. Chem. 2022, 14, 898–904.

5. Cheng, Q.; Chen, J.; Lin, S.; Ritter, T.* “Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines.” J. Am. Chem. Soc. 2020, 142, 17287–17293.

6. Cheng, Q.; Ritter, T.* “New Directions in C–H Fluorination.” Trends Chem. 2019, 1, 461–470.

7. Cheng, Q.; Xie, J.-H.; Weng, Y.-C.; You, S.-L.* “Pd-Catalyzed Dearomatization Reaction of Anthranils with Vinylcyclopropanes via [4+3] Cyclization Reaction.” Angew. Chem. Int. Ed. 2019, 58, 5739–5743.

8. Cheng, Q.;# Tu, H.-F.;# Zheng, C.; Qu, J.-P.; Helmchen, G.; You, S.-L.* “Iridium-Catalyzed Asymmetric Allylic Substitution Reactions.” Chem. Rev. 2019, 119, 1855–1969. (#co-first author)

9. Cheng, Q.; Zhang, F.; Cai, Y.; Guo, Y.-L.*; You, S.-L.* "Stereodivergent Synthesis of Tetrahydrofuroindoles via Palladium-Catalyzed Asymmetric Dearomative Formal [3+2] Cycloaddition Reactions." Angew. Chem. Int. Ed. 2018, 57, 2134–2138.

10. Cheng, Q.; Zhang, H.-J.; Yue, W.-J.; You, S.-L.* "Palladium-Catalyzed Highly Stereoselective Dearomative [3+2] Cycloaddition of Nitrobenzofurans." Chem 2017, 3, 428–436.

11. Cheng, Q.* "Natural-Product-Inspired Dearomatization of Nitrobenzofurans." Chem 2017, 3, 380–382.

12. Cheng, Q.; Wang, Y.; You, S.-L.* "Chemo-, Diastereo- and Enantioselective Iridium-Catalyzed Allylic Intramolecular Dearomatization Reaction of Naphthol Derivatives." Angew. Chem. Int. Ed. 2016, 55, 3496–3499.