Our research team employs interdisciplinary methods, encompassing structural biology, cell biology, and medicinal chemistry, to unravel the molecular basis of channelopathies and explore diverse modes of action for drugs targeting ion channels.
Currently, invasive fungal infections are devastating due to the widespread use of broad-spectrum antibiotics and interventional treatment. Among them, Candida albicans is one of the most prevalent opportunistic pathogenic fungi in the humans, responsible for 60-70% of invasive fungal infections.
Wang Yan is the Chief Researcher and Professor of the School of Life Sciences at Taikang Life Medicine Center of Wuhan University, mainly researching blood lipid abnormalities
My research interest focuses on developing novel technologies for DNA methylation analysis using chemical and biochemical approaches, with a primary application in the field of cancer early screening and related biomedical research.
Prion diseases primarily caused by the conformational conversion of prion protein (PrP) from its cellular form (PrPC) into a pathological aggregated form (PrPSc) in humans, cattle, sheep and cervid species. A major pathological hallmark of Amyotrophic lateral sclerosis (ALS) is the aggregates formed by copper, zinc superoxide dismutase (SOD1) in motor neuron cells.
E-mail:ying.zhang84@whu.edu.cnBiographyEDUCATION AND APPOINTMENTS2018- Professor, Medical Research Institute, Wuhan University, China2015-2018, Senior Scientist, Group Lead of HDR in HSC, CRISPR Therapeutics Inc.2012-2015, Postdoctoral fellow, Dept. of Genetics, Harvard Medical School2006-2012, Ph.D. in Cell, Stem Cell, and Developmental Biology, University of Colorado Anschutz Medical Campus2002-...