Currently, immune therapies targeting the PD-1/PD-L1 pathway are widely employed in clinical oncology. While these treatments result in complete remission for specific cancer patients, a considerable proportion, around 70%, do not respond as expected. Therefore, the search for new strategies in cancer immunotherapy have become hot topics and cutting-edge issues in cancer research.
1. Functional biomaterials for periodontal regeneration, The National Science Fund for Distinguished Young Scholars (82025011), 01/2021-12/2025 2. Study on the regulation of periodontal microecology and periodontal regeneration by biomimetic bone electrically active materials, The National Key Research and Development Program, 12/2021-11/2024
E-mail：zhentaozhang@whu.edu.cnWebsite：https://tkclms.whu.edu.cn/info/1179/1249.htmBiographyEducation09/2007-06/2010 Tongji Medical College, Huazhong University of Science and Technology. Doctor’s degree in neurology.09/2004-06/2007 Tongji Medical College, Huazhong University of Science and Technology. Master’s degree in neurology.09/1999-06/2004 Weifang Medical College. Batcher’s degree in ...
Zhuzhen Zhang earned her B.S. from Department of Applied Chemistry of Chang’an University and Ph.D. degree from Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. She performed her Ph.D. research in areas of iron metabolism in Fudi Wang’s lab, and started the early career planning in Jiarui Wu’s lab in SIBS. She completed postdoctoral training in skin and adipocytes research in Richard C. Wang and Philipp E. Scherer’s laboratories at UT Southwestern Medical Center from 2015-2021.
Dr. Zhong’s research interest is focused on the mechanisms and targeted therapy of infection-related inflammation, autoimmunity, and tumorigenesis and metastasis. His group has characterized several key proteins involved in ubiquitination and deubiquitination-mediated temporal and spatial regulatory mechanisms of antiviral immune signaling and inflammation. In addition, he has demonstrated that these key molecules and mechanisms are involved in autoimmunity and tumorigenesis and that targeting these molecules effectively inhibits the progression of autoimmune diseases and cancers. These findings not only advance the understanding of inflammation and tumorigenesis, but also provide potential therapeutic strategies for the related diseases.
E-mail：qhzhou@whu.edu.cnWebsite：qhzhou.whu.edu.cnBiographyWorking Experience:2015-present, Wuhan University, Professor2011-2015, the Scripps Research Institute (with Prof. Phil S Baran)2010-2011, SIOC, Research Associate (with Prof. Dawei Ma)Education and Training:2005-2010, Shanghai Institute of Organic Chemistry, PhD (supervisor Prof. Dawei Ma)2001-2005, Peking University, BS (supervisor Prof. ...
